ABSTRACT
Introduction: The purpose of this study was to find outthe prevalence of oral lichen planus in those diabeticpatients who visited dental department of communityhealth centre (Gousia hospital, khanyar) Srinagar, Kashmir,India from January 2016 to Sept 2017. Diabetic patientswith a homogenous range of age, gender and race wereexamined for presence of clinical oral lichen planus.Patient medication histories were additionally obtained.Material and methods: 1000 diabetes patients were enrolledfor the study. The subjects were examined for the presence/absence of oral lichen planus and the data was recorded andanalysed.Results: Out of 1000 diabetic patients 12 (1.2%) werehaving oral lichen planus and 11 patients belonged to type IIdiabetes mellitus. Among the subjects suffering from Type IDiabetes, only one patient was diagnosed of having oral lichenplanus. Out of 12 (1.2%) patients having oral lichen planusfour patients were having high blood pressure suggestingGrinspan’s syndrome (33.3%).Conclusion: The prevalence of oral lichen planus amongdiabetic patients was found to be 1.2%; additionally somepatients had high blood pressure, that suggests the existenceof Grinspan’s syndrome. Many studies conducted previously,suggest that psychosomatic factors such as stress and anxietyare attributed to lichen planus and therefore the diabeticpatients may get exposed to such factors thereby developingoral lichen planus.
ABSTRACT
Background: Various grading systems have been suggested in the literature by different authors to determine the severity of dysplastic features. Histopathological grading is subjective with low reproductivity and lacks sensitivity. Aim: To determine the inter observer and intra observer variability in diagnosing oral epithelial dysplasia using different grading systems. Materials and methods: Three oral pathologists from the Department the Oral pathology, GDC Srinagar observed the same 30 consecutive sections of oral epithelial dysplasia. Each reviewing pathologist asked to grade each case on the basis of WHO (2005) and binary grading system (2006) at different time intervals and was repeated twice. Results: The inter observer variability ranged from poor to slight in WHO system and slight to fair in binary system whereas the intra observer variability ranged from slight to fair in WHO system and fair in the binary system. Conclusion: Grading of oral epithelial dysplasia is subjective and has been shown not to be highly reproducible. The binary grading system verified to have better inter observer and intra observer agreement in the present study than the WHO grading system.
ABSTRACT
Background: Hepatitis B and Hepatitis C are the blood-borne diseases with high morbidity and mortality. These are responsible for liver diseases, cirrhosis and hepatocellular carcinoma so determination of hematological parameters is essential in these patients. The aim of the present study was to compare the change in the hematological parameters in patients with hepatitis B and C than those of healthy individuals. Material and methods: A case-control study was carried out by the routine screening of the hepatitis B and C patients by using rapid immunoassay test. The study group comprised of 15 cases of Hepatitis B positive, 15 cases of Hepatitis C positive and 15 cases of healthy individuals. Blood samples were collected from the patients with seropositive hepatitis B and C as well as healthy individuals to determine the variation in the hematological parameters. Results: Variation in the hematological parameters has been observed in patients with seropositive Hepatitis B and C virus as compared to healthy individuals. Conclusion: This study determines the need for routine hematological investigations in seropositive hepatitis B and C patients. Follow up of patients even after recovery from Hepatitis B and C virus infection should create an essential part of these patients’ management.
ABSTRACT
Ameloblastic carcinoma is an uncommon malignant odontogenic tumor of jaws and is a highly aggressive tumor with rapid growth and also a high potential for distant metastasis. Th e most common site of occurrence is posterior mandible. Clinically, it is aggressive and has potential for local destruction. Th e majority of the cases arise de novo, while few cases arise from a pre-existing ameloblastoma. Th e radiological feature of the ameloblastic carcinoma is usually similar to that of ameloblastoma except for the presence of focal radiopacity, which apparently refl ects dystrophic calcifi cation. Herein, we report a case of ameloblastic carcinoma in the left mandible of a 60-year-old female patient.
ABSTRACT
Odontogenic keratocyst was the first illustrated by Phillipsen in 1956 and is unique as it is aggressive locally, and rate of recurrence is high along with histological appearance which is very characteristic. It is a benign neoplasm of jaw with the diverse origin and its occurrence in maxilla is uncommon. We present a case of 30-year-old male with aggressive keratocystic odontogenic tumor (KCOT) in the right maxillary molar region. On radiological examination, radiolucent area, mimicking radicular cyst, was found in relation with maxillary first molar. A final diagnosis of KCOT was confirmed after histopathological findings. The clinical, radiological, and histopathological features of this tumor along with surgical management have been discussed.